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Current Issue of SCIENCE


Contents | Science 374, 6567
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COVER Sleep is an essential physiological process. Our bodies may be quiet and largely immobile, but our brains are highly active. Metabolites and other toxins that have accumulated over the course of the day get cleared away. Recent memories become consolidated. Scientists have thus begun to investigate the restorative and beneficial functions of sleep in great detail. See the special section beginning on page 550.

Illustration: Dion MBD

Science

  • Volume 374|
  • Issue 6567|
  • 29 Oct 2021

COVER Sleep is an essential physiological process. Our bodies may be quiet and largely immobile, but our brains are highly active. Metabolites and other toxins that have accumulated over the course of the day get cleared away. Recent memories become consolidated. Scientists have thus begun to investigate the restorative and beneficial functions of sleep in great detail. See the special section beginning on page 550.

Illustration: Dion MBD
Special issue

Sleep

Introduction to Special Issue

    BY
    • Peter Stern
  • : 550-551
  • FULL ACCESS

News

    BY
    • Rodrigo Pérez Ortega
  • : 552-555
  • FULL ACCESS
Poor sleep disproportionately undermines the health of communities of color. Researchers want to figure out why—and find solutions

Reviews

    BY
    • Nicholas P. Franks
    • William Wisden
  • : 556-559
  • FULL ACCESS
    BY
    • Gabrielle Girardeau
    • Vítor Lopes-dos-Santos
  • : 560-564
  • FULL ACCESS
    BY
    • Laura D. Lewis
  • : 564-568
  • FULL ACCESS
    BY
    • Michael A. Grandner
    • Fabian-Xosé Fernandez
  • : 568-573
  • FULL ACCESS

Editorial

    BY
    • Ramón Pichs Madruga
  • : 511-511
  • FULL ACCESS

In Brief

    BY
    • : 516-517
    • FULL ACCESS

    In Depth

      BY
      • Meredith Wadman
    • : 518-519
    • FULL ACCESS
    European Union countries are holdouts against widespread practice of adding folic acid to flour
      BY
      • Jyoti Madhusoodanan
    • : 519-519
    • FULL ACCESS
    Scientists started fewer new research projects in 2020
      BY
      • Robert F. Service
    • : 520-521
    • FULL ACCESS
    Study slammed by critic, who has demanded raw data withheld by authors
      BY
      • Michael Price
    • : 521-522
    • FULL ACCESS
    Data from Tanis site—claimed to preserve the Cretaceous extinction—impress some geologists, but skeptics remain
      BY
      • Kai Kupferschmidt
    • : 522-523
    • FULL ACCESS
    Scientists like Devi Sridhar leaped to fill an information gap
      BY
      • Jocelyn Kaiser
    • : 524-524
    • FULL ACCESS
    Some observers say White House should drop that tradition to broaden the candidate pool

    Feature

      BY
      • Elizabeth Pennisi
    • : 526-529
    • FULL ACCESS
    Evidence from evolutionarily ancient creatures is revealing that sleep is not just for the brain

    Working Life

      BY
      • Katharina Maisel
    • : 650-650
    • FULL ACCESS

    Letters

      BY
      • U. Rashid Sumaila
      • Daniel J. Skerritt
      • Anna Schuhbauer
      • Sebastian Villasante
      • Andrés M. Cisneros-Montemayor
      • Hussain Sinan
      • Duncan Burnside
      • Patrízia Raggi Abdallah
      • Keita Abe
      • Kwasi A. Addo
      • Julia Adelsheim
      • Ibukun J. Adewumi
      • Olanike K. Adeyemo
      • Neil Adger
      • Joshua Adotey
      • Sahir Advani
      • Zahidah Afrin
      • Denis Aheto
      • Shehu L. Akintola
      • Wisdom Akpalu
      • Lubna Alam
      • Juan José Alava
      • Edward H. Allison
      • Diva J. Amon
      • John M. Anderies
      • Christopher M. Anderson
      • Evan Andrews
      • Ronaldo Angelini
      • Zuzy Anna
      • Werner Antweiler
      • Evans K. Arizi
      • Derek Armitage
      • Robert I. Arthur
      • Noble Asare
      • Frank Asche
      • Berchie Asiedu
      • Francis Asuquo
      • Lanre Badmus
      • Megan Bailey
      • Natalie Ban
      • Edward B. Barbier
      • Shanta Barley
      • Colin Barnes
      • Scott Barrett
      • Xavier Basurto
      • Dyhia Belhabib
      • Elena Bennett
      • Nathan J. Bennett
      • Dominique Benzaken
      • Robert Blasiak
      • John J. Bohorquez
      • Cesar Bordehore
      • Virginie Bornarel
      • David R. Boyd
      • Denise Breitburg
      • Cassandra Brooks
      • Lucas Brotz
      • Donovan Campbell
      • Sara Cannon
      • Ling Cao
      • Juan C. Cardenas Campo
      • Steve Carpenter
      • Griffin Carpenter
      • Richard T. Carson
      • Adriana R. Carvalho
      • Mauricio Castrejón
      • Alex J. Caveen
      • M. Nicole Chabi
      • Kai M. A. Chan
      • F. Stuart Chapin
      • Tony Charles
      • William Cheung
      • Villy Christensen
      • Ernest O. Chuku
      • Trevor Church
      • Colin Clark
      • Tayler M. Clarke
      • Andreea L. Cojocaru
      • Brian Copeland
      • Brian Crawford
      • Anne-Sophie Crépin
      • Larry B. Crowder
      • Philippe Cury
      • Allison N. Cutting
      • Gretchen C. Daily
      • Jose Maria Da-Rocha
      • Abhipsita Das
      • Santiago de la Puente
      • Aart de Zeeuw
      • Savior K. S. Deikumah
      • Mairin Deith
      • Boris Dewitte
      • Nancy Doubleday
      • Carlos M. Duarte
      • Nicholas K. Dulvy
      • Tyler Eddy
      • Meaghan Efford
      • Paul R. Ehrlich
      • Laura G. Elsler
      • Kafayat A. Fakoya
      • A. Eyiwunmi Falaye
      • Jessica Fanzo
      • Clare Fitzsimmons
      • Ola Flaaten
      • Katie R. N. Florko
      • Marta Flotats Aviles
      • Carl Folke
      • Andrew Forrest
      • Peter Freeman
      • Kátia M. F. Freire
      • Rainer Froese
      • Thomas L. Frölicher
      • Austin Gallagher
      • Veronique Garcon
      • Maria A. Gasalla
      • Jessica A. Gephart
      • Mark Gibbons
      • Kyle Gillespie
      • Alfredo Giron-Nava
      • Kristina Gjerde
      • Sarah Glaser
      • Christopher Golden
      • Line Gordon
      • Hugh Govan
      • Rowenna Gryba
      • Benjamin S. Halpern
      • Quentin Hanich
      • Mafaniso Hara
      • Christopher D. G. Harley
      • Sarah Harper
      • Michael Harte
      • Rebecca Helm
      • Cullen Hendrix
      • Christina C. Hicks
      • Lincoln Hood
      • Carie Hoover
      • Kristen Hopewell
      • Bárbara B. Horta e Costa
      • Jonathan D. R. Houghton
      • Johannes. A. Iitembu
      • Moenieba Isaacs
      • Sadique Isahaku
      • Gakushi Ishimura
      • Monirul Islam
      • Ibrahim Issifu
      • Jeremy Jackson
      • Jennifer Jacquet
      • Olaf P. Jensen
      • Jorge Jimenez Ramon
      • Xue Jin
      • Alberta Jonah
      • Jean-Baptiste Jouffray
      • S. Kim Juniper
      • Sufian Jusoh
      • Isigi Kadagi
      • Masahide Kaeriyama
      • Michel J. Kaiser
      • Brooks Alexandra Kaiser
      • Omu Kakujaha-Matundu
      • Selma T. Karuaihe
      • Mary Karumba
      • Jennifer D. Kemmerly
      • Ahmed S. Khan
      • Patrick Kimani
      • Kristin Kleisner
      • Nancy Knowlton
      • Dawn Kotowicz
      • John Kurien
      • Lian E. Kwong
      • Steven Lade
      • Dan Laffoley
      • Mimi E. Lam
      • Vicky W. L. Lam
      • Glenn-Marie Lange
      • Mohd T. Latif
      • Philippe Le Billon
      • Valérie Le Brenne
      • Frédéric Le Manach
      • Simon A. Levin
      • Lisa Levin
      • Karin E. Limburg
      • John List
      • Amanda T. Lombard
      • Priscila F. M. Lopes
      • Heike K. Lotze
      • Tabitha G. Mallory
      • Roshni S. Mangar
      • Daniel Marszalec
      • Precious Mattah
      • Juan Mayorga
      • Carol McAusland
      • Douglas J. McCauley
      • Jeffrey McLean
      • Karly McMullen
      • Frank Meere
      • Annie Mejaes
      • Michael Melnychuk
      • Jaime Mendo
      • Fiorenza Micheli
      • Katherine Millage
      • Dana Miller
      • Kolliyil Sunil Mohamed
      • Essam Mohammed
      • Mazlin Mokhtar
      • Lance Morgan
      • Umi Muawanah
      • Gordon R. Munro
      • Grant Murray
      • Saleem Mustafa
      • Prateep Nayak
      • Dianne Newell
      • Tu Nguyen
      • Frederik Noack
      • Adibi M. Nor
      • Francis K. E. Nunoo
      • David Obura
      • Tom Okey
      • Isaac Okyere
      • Paul Onyango
      • Maartje Oostdijk
      • Polina Orlov
      • Henrik Österblom
      • Dwight Owens
      • Tessa Owens
      • Mohammed Oyinlola
      • Nathan Pacoureau
      • Evgeny Pakhomov
      • Juliano Palacios Abrantes
      • Unai Pascual
      • Aurélien Paulmier
      • Daniel Pauly
      • Rodrigue Orobiyi Edéya Pèlèbè
      • Daniel Peñalosa
      • Maria G. Pennino
      • Garry Peterson
      • Thuy T. T. Pham
      • Evelyn Pinkerton
      • Stephen Polasky
      • Nicholas V. C. Polunin
      • Ekow Prah
      • Jorge Ramírez
      • Veronica Relano
      • Gabriel Reygondeau
      • Don Robadue
      • Callum Roberts
      • Alex Rogers
      • Katina Roumbedakis
      • Enric Sala
      • Marten Scheffer
      • Kathleen Segerson
      • Juan Carlos Seijo
      • Karen C. Seto
      • Jason F. Shogren
      • Jennifer J. Silver
      • Gerald Singh
      • Ambre Soszynski
      • Dacotah-Victoria Splichalova
      • Margaret Spring
      • Jesper Stage
      • Fabrice Stephenson
      • Bryce D. Stewart
      • Riad Sultan
      • Curtis Suttle
      • Alessandro Tagliabue
      • Amadou Tall
      • Nicolás Talloni-Álvarez
      • Alessandro Tavoni
      • D. R. Fraser Taylor
      • Louise S. L. Teh
      • Lydia C. L. Teh
      • Jean-Baptiste Thiebot
      • Torsten Thiele
      • Shakuntala H. Thilsted
      • Romola V. Thumbadoo
      • Michelle Tigchelaar
      • Richard S. J. Tol
      • Philippe Tortell
      • Max Troell
      • M. Selçuk Uzmanoğlu
      • Ingrid van Putten
      • Gert van Santen
      • Juan Carlos Villaseñor-Derbez
      • Colette C. C. Wabnitz
      • Melissa Walsh
      • J. P. Walsh
      • Nina Wambiji
      • Elke U. Weber
      • Frances Westley
      • Stella Williams
      • Mary S. Wisz
      • Boris Worm
      • Lan Xiao
      • Nobuyuki Yagi
      • Satoshi Yamazaki
      • Hong Yang
      • Dirk Zeller
    • : 544-544
    • FULL ACCESS
      BY
      • Madhav Thambisetty
      • Robert Howard
      • M. Maria Glymour
      • Lon S. Schneider
    • : 544-545
    • FULL ACCESS
    • : 546-546
    • FULL ACCESS

    Books et al.

      BY
      • Greger Larson
    • : 541-541
    • FULL ACCESS
    With few solid leads, a paleoanthropologist explores the emergence of the first dogs
      BY
      • Shane Campbell-Staton
    • : 542-542
    • FULL ACCESS
    Human interventions, both intentional and unintentional, define a new chapter in Earth’s storied history

    Essays

      BY
      • Amber L. Alhadeff
    • : 547-548
    • FULL ACCESS
    Interoceptive sensing and hunger neurons have a role in the control of behavior
      BY
      • Justin Rustenhoven
    • : 548-548
    • FULL ACCESS
    Local neuroimmune collaboration safeguards the central nervous system
      BY
      • Andreas J. Keller
    • : 548-548
    • FULL ACCESS
    Context controls the activity of sensory neurons

    Policy Forum

      BY
      • Gautam Rao
      • Susan Redline
      • Frank Schilbach
      • Heather Schofield
      • Mattie Toma
    • : 530-533
    • FULL ACCESS
    Evidence is particularly needed from poorer communities

    Perspectives

      BY
      • Virinder Reen
      • Jesús Gil
    • : 534-535
    • FULL ACCESS
    Cell cycle arrest produces a p21-dependent secretome that initiates immunosurveillance of premalignant cells
      BY
      • John Schoggins
    • : 535-536
    • FULL ACCESS
    Genetic variation in a sensor of double-stranded RNA can exacerbate COVID-19
      BY
      • Donald L. Fixico
    • : 536-537
    • FULL ACCESS
    A major data synthesis maps tribal displacements
      BY
      • Jiyun N. Shin
      • Guy Doron
      • Matthew E. Larkum
    • : 538-539
    • FULL ACCESS
    Cortical layer 1 has a special role in long-term memory
      BY
      • Margaret J. Sobkowicz
    • : 540-540
    • FULL ACCESS
    Addition of keto groups to polyethylene helps it degrade while maintaining its properties

    Association Affairs

      BY
      • Becky Ham
    • : 549-549
    • FULL ACCESS
    Vaccines, AI, and sexually transmitted infections among first topics
    • : 633-638
    • FULL ACCESS

    In Other Journals

      BY
      • Jesse Smith
      • Andrew M. Sugden
      • Yury Suleymanov
      • Brent Grocholski
      • Stella M. Hurtley
      • Priscilla N. Kelly
      • Ian S. Osborne
      • Beverly A. Purnell
    • : 575-576
    • FULL ACCESS
    Editors’ selections from the current scientific literature

    In Science Journals

      BY
      • H. Jesse Smith
      • Michael A. Funk
      • Di Jiang
      • Jelena Stajic
      • Phil Szuromi
      • Caroline Ash
      • Pamela J. Hines
      • Leslie K. Ferrarelli
      • Gemma Alderton
      • Seth Thomas Scanlon
      • Tage S. Rai
      • Jake Yeston
      • Ian S. Osborne
      • Claire Olingy
      • Courtney S. Malo
      • Mark Aldenderfer
    • : 574-576
    • FULL ACCESS
    Highlights from the Science family of journals

    Reports

      BY
      • Guilhem Sommeria-Klein
      • Romain Watteaux
      • Federico M. Ibarbalz
      • Juan José Pierella Karlusich
      • Daniele Iudicone
      • Chris Bowler
      • Hélène Morlon
    • : 594-599
    • FULL ACCESS
    Eukaryotic plankton biogeography and its determinants at global scale reflect differences in ecology and body size.
      BY
      • Dongfeng Li
      • Xixi Lu
      • Irina Overeem
      • Desmond E. Walling
      • Jaia Syvitski
      • Albert J. Kettner
      • Bodo Bookhagen
      • Yinjun Zhou
      • Ting Zhang
    • : 599-603
    • FULL ACCESS
    The flux of sediments from rivers in High Mountain Asia has increased substantially over the past 60 years.
      BY
      • Maximilian Baur
      • Fei Lin
      • Tobias O. Morgen
      • Lukas Odenwald
      • Stefan Mecking
    • : 604-607
    • FULL ACCESS
    A nickel catalyst adds just enough CO into polyethylene chains to improve degradation without compromising other properties.
      BY
      • Koen M. Bastiaans
      • Damianos Chatzopoulos
      • Jian-Feng Ge
      • Doohee Cho
      • Willem O. Tromp
      • Jan M. van Ruitenbeek
      • Mark H. Fischer
      • Pieter J. de Visser
      • David J. Thoen
      • Eduard F. C. Driessen
      • Teunis M. Klapwijk
      • Milan P. Allan
    • : 608-611
    • FULL ACCESS
    Tunneling noise spectroscopy was used to measure the effective charge of carriers in titanium nitride.
      BY
      • Julian Karst
      • Moritz Floess
      • Monika Ubl
      • Carsten Dingler
      • Claudia Malacrida
      • Tobias Steinle
      • Sabine Ludwigs
      • Mario Hentschel
      • Harald Giessen
    • : 612-616
    • FULL ACCESS
    A metallic polymer is used for the electrical switching of plasmonic nanoantennas.
      BY
      • Amilcar Bedoya-Pinto
      • Jing-Rong Ji
      • Avanindra K. Pandeya
      • Pierluigi Gargiani
      • Manuel Valvidares
      • Paolo Sessi
      • James M. Taylor
      • Florin Radu
      • Kai Chang
      • Stuart S. P. Parkin
    • : 616-620
    • FULL ACCESS
    x-ray magnetic circular dichroism measurements indicate ferromagnetism in monolayer CrCl3 grown on graphene.
      BY
      • Jingwei Hou
      • Peng Chen
      • Atul Shukla
      • Andraž Krajnc
      • Tiesheng Wang
      • Xuemei Li
      • Rana Doasa
      • Luiz H. G. Tizei
      • Bun Chan
      • Duncan N. Johnstone
      • Rijia Lin
      • Tobias U. Schülli
      • Isaac Martens
      • Dominique Appadoo
      • Mark S’ Ari
      • Zhiliang Wang
      • Tong Wei
      • Shih-Chun Lo
      • Mingyuan Lu
      • Shichun Li
      • Ebinazar B. Namdas
      • Gregor Mali
      • Anthony K. Cheetham
      • Sean M. Collins
      • Vicki Chen
      • Lianzhou Wang
      • Thomas D. Bennett
    • : 621-625
    • FULL ACCESS
    A composite of a lead halide perovskite and a metal-organic framework glass exhibits bright and stable photoluminescence.
      BY
      • Suyu Jiang
      • Marie-Françoise Jardinaud
      • Jinpeng Gao
      • Yann Pecrix
      • Jiangqi Wen
      • Kirankumar Mysore
      • Ping Xu
      • Carmen Sanchez-Canizares
      • Yiting Ruan
      • Qiujiu Li
      • Meijun Zhu
      • Fuyu Li
      • Ertao Wang
      • Phillip S. Poole
      • Pascal Gamas
      • Jeremy D. Murray
    • : 625-628
    • FULL ACCESS
    NLP regulation of leghemoglobins in N-fixing nodules descended from an ancient NLP-hemoglobin regulatory module.
      BY
      • Jian Feng
      • Tak Lee
      • Katharina Schiessl
      • Giles E. D. Oldroyd
    • : 629-632
    • FULL ACCESS
    A transcription factor first functions intact and later as a fragment to regulate separate phases of root nodule development.

    Research Articles

      BY
      • Ines Sturmlechner
      • Cheng Zhang
      • Chance C. Sine
      • Erik-Jan van Deursen
      • Karthik B. Jeganathan
      • Naomi Hamada
      • Jan Grasic
      • David Friedman
      • Jeremy T. Stutchman
      • Ismail Can
      • Masakazu Hamada
      • Do Young Lim
      • Jeong-Heon Lee
      • Tamas Ordog
      • Remi-Martin Laberge
      • Virginia Shapiro
      • Darren J. Baker
      • Hu Li
      • Jan M. van Deursen
    • FULL ACCESS
    The cell cycle factor p21 concurrently induces proliferative arrest and immunosurveillance of cells under stress, controlling their fate.
      BY
      • Justin Farrell
      • Paul Berne Burow
      • Kathryn McConnell
      • Jude Bayham
      • Kyle Whyte
      • Gal Koss
    • FULL ACCESS
    A dataset of Indigenous land dispossession and forced migration compares historical with present-day tribal lands.
      BY
      • Arthur Wickenhagen
      • Elena Sugrue
      • Spyros Lytras
      • Srikeerthana Kuchi
      • Marko Noerenberg
      • Matthew L. Turnbull
      • Colin Loney
      • Vanessa Herder
      • Jay Allan
      • Innes Jarmson
      • Natalia Cameron-Ruiz
      • Margus Varjak
      • Rute M. Pinto
      • Jeffrey Y. Lee
      • Louisa Iselin
      • Natasha Palmalux
      • Douglas G. Stewart
      • Simon Swingler
      • Edward J. D. Greenwood
      • Thomas W. M. Crozier
      • Quan Gu
      • Emma L. Davies
      • Sara Clohisey
      • Bo Wang
      • Fabio Trindade Maranhão Costa
      • Monique Freire Santana
      • Luiz Carlos de Lima Ferreira
      • Lee Murphy
      • Angie Fawkes
      • Alison Meynert
      • Graeme Grimes
      • ISARIC4C Investigators
      • Joao Luiz Da Silva Filho
      • Matthias Marti
      • Joseph Hughes
      • Richard J. Stanton
      • Eddie C. Y. Wang
      • Antonia Ho
      • Ilan Davis
      • Ruth F. Jarrett
      • Alfredo Castello
      • David L. Robertson
      • Malcolm G. Semple
      • Peter J. M. Openshaw
      • Massimo Palmarini
      • Paul J. Lehner
      • J. Kenneth Baillie
      • Suzannah J. Rihn
      • Sam J. Wilson
    • Open Access
    A component of the human interferon system that activates SARS-CoV-2 cellular defenses appears to be defective in a large proportion of humans.
      BY
      • François A. Thélot
      • Wenyi Zhang
      • KangKang Song
      • Chen Xu
      • Jing Huang
      • Maofu Liao
    • : 580-585
    • FULL ACCESS
    Cryo–electron microscopy structures reveal distinct binding modes and inhibition mechanisms of bacterial lipid transporters.
      BY
      • Yodai Takei
      • Shiwei Zheng
      • Jina Yun
      • Sheel Shah
      • Nico Pierson
      • Jonathan White
      • Simone Schindler
      • Carsten H. Tischbirek
      • Guo-Cheng Yuan
      • Long Cai
    • : 586-594
    • FULL ACCESS
    Multimodal measurements in single cells in the brain reveal nuclear organization principles across cell types.

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