Post-doctoral position - University of California, Berkeley - Human Evolutionary Genetics. Description: The Moorjani Lab (https://moorjanilab.org/) at the University of California, Berkeley uses computational and statistical methods to investigate questions in human evolutionary genetics, in particular to understand mutation rate evolution, demographic inference and archaic ancestry. A central aim in the lab is to understand the impact of evolutionary history on genetic variation and to apply this knowledge to learn about human history and disease. To this end, we use genetic data from ancient specimens and present-day species to learn about: (1) when key evolutionary events--e.g, introgression and adaptation--occurred in human history, (2) how different evolutionary processes such as mutation rate evolve across primates, and (3) how we can leverage these patterns to identify genetic variants related to human adaptation and disease. The research in the lab involves both development of new methods and large-scale genomic data analysis. Recent publications from our lab: Kerdoncuff E*, Skov L*, Patterson N, Banerjee J, Khobragade P, , Chakrabarti SS, Chakrawarty A, Chatterjee P, Dhar M, Gupta M, John JP, Koul PA, Lehl SS, Mohanty RR, Padmaja M, Perianayagam A 12, Rajguru C, Sankhe L, Talukdar A, Varghese M, Yadati SR, Zhao W, Leung YY, Schellenberg GD, Wang YZ, Smith JA, Dey S, Ganna A , Dey AB, Kardia SLR, Lee J, Moorjani P. 50,000 years of Evolutionary History of India: Impact on Health and Disease Variation. Cell 188 (2025):13, 3389-3404.e6. Iasi LM*, Chintalapati M*, Skov L , Mesa AB , Hajdinjak M, Peter BM, Moorjani P. Neandertal ancestry through time: Insights from genomes of ancient and present-day humans. Science 386.6727 (2024): eadq3010. Gao Z, Zhang Y, Cramer N, Przeworski M, Moorjani P. Limited role of generation time changes in driving the evolution of the mutation spectrum in humans. eLife (2023):12, e81188. Responsibilities: A successful candidate will develop and apply computational approaches to large genomic datasets to characterize patterns of population history and evolution. The main responsibilities include conducting research, attending regular lab meetings and journal clubs, and preparing research results for publication and presentations at scientific meetings. Opportunities may also exist for mentoring graduate and undergraduate students. Required qualifications: Ph.D. or equivalent in genetics, genomics, computational biology or related fields and demonstrated record of productivity and publications. Experience with programming (e.g. C/C++, Python/ Perl, R or other programming languages), genomic data analysis and methods development. Please contact Priya with your CV and a brief overview of research questions you are interested in pursuing. Please also request three recommenders to send a letter of reference on your behalf. The position is open until filled. Salary: This is a multi-year postdoctoral position (initial appointment is for 24 months and renewable annually up to two more years). Salary is commensurate with qualifications and experience. Contact: Priya Moorjani Assistant Professor Department of Molecular and Cell Biology Center for Computational Biology https://moorjanilab.org/ Email: moorjani@berkeley.edu Priya G Moorjani (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)