Dear all, registrations are now open for the online course on Manuel Genome Curation using PretextView. Dates: 11th - 15th November Course website: ( https://www.physalia-courses.org/courses-workshops/genome-curation/ ) Our course will introduce biologists and bioinformaticians to the concepts of manual genome curation using PretextView, through theoretical knowledge and practical examples. We will start introducing the concept of Hi-C sequencing and why this data is important to genome curation. Some steps prior to genome curation also will be addressed, such as the sort of information we can obtain from assembly quality metrics and the relevance of decontaminating your assembly before curation. Points such as how to generate a genome curated fasta file and strategies used to curate more challenging genomes will also be explored during the course. Finally, we will show how to identify sex chromosomes and some additional tools helpful for curation. By the end of the course, students will be familiar with manual genome curation, enabling them to interpret and work with Hi-C maps. In addition, they will understand everything that is needed to deliver high-quality chromosome assemblies. After atteding this course, participants will be able to: Understand how the assembly and Hi-C data quality are vital for efficient genome curation. Interpret Hi-C heatmaps in PretextView and identify the edits necessary to fix assembly errors. Use PretextView and its features for manual curation. Obtain a genome curated fasta file using the Rapid Curation pipeline. Use additional tools to curate more challenging genomes (microchromosomes, high heterozygosity) and how to identify sex chromosomes. For the full list of our courses and workshops, please visit: ( https://www.physalia-courses.org/courses-workshops/genome-curation/ ) Best regards, Carlo Carlo Pecoraro, Ph.D Physalia-courses DIRECTOR info@physalia-courses.org mobile: +49 17645230846 "info@physalia-courses.org" (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)