Dear all, We are pleased to announce an upcoming online course titled "Structural Variant Detection and Comparison", scheduled for 2-4 December. This course will introduce biologists and bioinformaticians into the field of Structural Variant (SV) detection and comparison. Course website: (https://www.physalia-courses.org/courses-workshops/svs/) This course will cover a broad spectrum of software and analysis workflows, from short to long-read approaches, using assembly or mapping-based methods to identify these variants. Participants will gain insights into filtering and assessing SVs, generating trio/population-level VCF files, and evaluating their functional impact. The course will also offer guidance on how to prioritize, rank, and QC these variants further. The course is structured in modules over three days, with each day featuring an introductory lecture followed by practical, hands-on sessions. These sessions will include mirroring exercises with the instructor and individual exercises to reinforce learning. Group discussions will follow each exercise to interpret results. This course is ideal for researchers interested in genomic comparisons and understanding the implications of genomic similarities and variations. Both beginners and advanced users will benefit, starting with general concepts of comparative genomics and progressing through all major analysis steps. Participants should have a background in biology, basic familiarity with genomic data, and some experience with Linux command line tools. By the end of the course, participants will be able to: - Identify Structural Variants using mapping or assembly approach - Identify Structural Variants from long and short read data. - Compare and filtering Structural Variants. - Annotate of Structural Variants (gene overlap, Population frequency) - Generate a trio / population VCF file for Structural Variants - Identify mosaic / somatic Structural Variants For the full list of our courses and workshops, please visit: (https://www.physalia-courses.org/courses-workshops) Best regards, Carlo Carlo Pecoraro, Ph.D Physalia-courses DIRECTOR info@physalia-courses.org mobile: +49 17645230846 "info@physalia-courses.org" (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)